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Ethanol


Other Names:

Ethyl alcohol







General Information:


Structure:



CAS Number: 64-17-5

Molecular Weight: 46.07 g/mol

Appearance: Colorless liquid

Melting Point: -114 C

Boiling Point: 78.3 C

Density: 0.789 g/mL at 25 C


Pure ethanol (absolute, 200 proof) is very expensive due to the fact that alcohol products are heavily taxed. Denatured ethanol is considerably cheaper than absolute ethanol. The ethanol used in most labs has been denatured by adding things such as isopropanol or methanol. Denatured ethanol is not suitable for consumption.




Common Uses:


Reagent in Fisher esterifications





Reagent in Pinner reactions





Solvent for reactions





Solvent for silica gel column chromatography



Procedure excerpt:

…volatiles were removed in vacuo and the crude material was purified via Prep MPLC (100 g SNAP cartridge, 0-5% EtOH/DCM) to provide…




Solvent for triturations



Procedure excerpt:

…Trituration from cold EtOH provided the product as a white solid…




Safety:


Ethanol is a flammable liquid. Drinking denatured ethanol is dangerous. For example, if it has been denatured with methanol then blindness or death could result.




References:


1) WO2014149164, page 299

2) WO2015129926, page 83

3) WO2014149164, page 375

4) WO2016012477, page 152

5) WO2014177977, page 66

6) Wikipedia: Ethanol (link)

7) www.sigmaaldrich.com: Ethanol (link)