Alkene to Alcohol

(Cleavage)

Common Conditions:

Ozone + NaBH₄

Reaction of alkenes with ozone, followed by the quenching of the ozonide intermediate with sodium borohydride (NaBH4) results in the overall cleavage of an alkene to an alcohol.^[1]

Examples

Reaction Map:

The reaction map is intended to provide insight into possible reactions one step before and after the title reaction. It also serves as an alternative way to navigate the website, and as a means of coming up with retrosynthetic ideas. Click on the reaction arrow to visit the page.

References:

1) Caron, S.; Practical Synthetic Organic Chemistry