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Pd2(dba)3

Tris(dibenzylideneacetone)dipalladium(0)










General Information:


Structure:



CAS Number: 51364-51-3

Molecular Weight: 915.72 g/mol

Appearance: Dark purple/brown solid




Common Uses:


Catalyst for a wide variety of Pd catalyzed couplings (ex. Suzuki)



Procedure excerpt:

The Iodo compound (308 mg, 0.513 mmol), the boronic ester (194 mg, 0.641 mmol), K3PO4 (327 mg, 1.539 mmol), XPhos (14.67 mg, 0.031 mmol), and Pd2(dba)3 . . .

[full procedure]




Catalyst for a wide variety of Pd catalyzed couplings (ex. Buchwald)



Procedure excerpt:

. . . dry powdered Cs2CO3 (15 mg, 0.046 mmol), Xantphos (4 mg, 0.007 mmol), and Pd2(dba)3 (4 mg, 0.004 mmol). Dry THF (1.5 mL) was then added and the mixture . . .

[full procedure]




Catalyst for a wide variety of Pd catalyzed couplings (ex. cyanation)



Procedure excerpt:

. . . the SM (16.53 g, 72 mmol) in DMF (20 mL) was added dppf (8 g, 14.43 mmol) and ZnCN2 (5.08 g, 43.3 mmol), followed by Pd2(dba)3 (6.61 g, 7.22 mmol). The mixture . . .

[full procedure]




Catalyst for a wide variety of Pd catalyzed couplings (ex. Stille)



Procedure excerpt:

To a mixture of the bromide (500 mg, 2.00 mmol), CsF (668 mg, 4.40 mmol), P(n-Bu)3 in hexane (0.347 mL, 0.120 mmol), Pd2(dba)3 (36.6 mg, 0.040 mmol), and toluene . . .

[full procedure]




References:


1) Patent Reference: WO2012129338, page 69, (12.0 MB)

2) Patent Reference: WO2012112946, page 187, (11.2 MB)

3) Patent Reference: WO2010032200, page 132, (6.2 MB)

4) Patent Reference: WO2011017578, page 129, (8.3 MB)

5) Wikipedia: Tris(dibenzylideneacetone)dipalladium(0) (link)

6) www.sigmaaldrich.com: Tris(dibenzylideneacetone)dipalladium(0) (link)