New Jobs:

- Research Chemist (Heritage)

- Oligonuc Chemist (Amgen)

- Scientist (Cayman)

- Sr Scientist (Takeda)

Latest Internships:

- Cayman Chemical

  (Bio-Organic Chemistry)

- Complete Genomics


Thionyl Chloride

Other Names:

Sulfurous oxychloride

Sulfurous dichloride

Thionyl dichloride

General Information:


CAS Number: 7719-09-7

Molecular Weight: 118.97 g/mol

Appearance: Clear liquid

Chemical Formula: SOCl2

Melting Point: -105 C

Boiling Point: 79 C

Density: 1.631 g/mL

Common Uses:

Reagent for converting carboxylic acids to acid chlorides

Reagent for converting carboxylic acids to esters

Reagent for converting alcohols to chlorides

Reagent for dehydrating primary amides to form nitriles


1) Patent Reference: WO2010016005, page 89, (11.3 MB)

2) Patent Reference: WO2010038081, page 128, (33.8 MB)

3) Patent Reference: WO2016014463, page 91, (6.7 MB)

4) Patent Reference: WO2010104899, page 155, (6.7 MB)

5) Wikipedia: Thionyl chloride (link)

6) Thionyl chloride (link)