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Sodium Carbonate


Other Names:

Carbonic acid disodium salt







General Information:


Structure:



CAS Number: 497-19-8

Molecular Weight: 105.99 g/mol

Appearance: White powder


Sodium carbonate (Na2CO3) is a moderately strong base used commonly in organic chemistry. It is regularly employed as the base of choice for palladium catalyzed reactions such as Suzuki couplings. Sodium carbonate is also used for other reactions that require a base to neutralize acids that form during reactions. For example, alkylation reactions often employ sodium carbonate to mop up protons (acid) that forms during the reaction.




Common Uses:


- Base for various reactions (ex. Suzuki reactions & alkylation reactions)

- Neutralization agent (ex. to neutralize a reaction mixture prior to work-up)




Safety:


Sodium carbonate (Na2CO3) is relatively non-toxic. For example, it is used for various purposes in the food and cosmetics industry. Sodium carbonate is a moderately strong base. It is a major irritant to skin and eyes. Store sodium carbonate separately from acids. Reactions with acids can be exothermic. Sodium carbonate is incompatible with aluminum.




References:


1) Wikipedia: Sodium carbonate (link)

2) www.sigmaaldrich.com: Sodium carbonate (link)