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Zinc










General Information:


Structure:


Zn


CAS Number: 7440-66-6

Molecular Weight: 65.39 g/mol

Appearance: Silver-gray solid


Zinc is a low cost reagent that is used in a wide variety of reduction reactions and in the making of organozinc reagents that allow the formation of new carbon-carbon bonds. Zinc sometimes requires activation before use.




Common Uses:


Reagent for reduction of nitro groups to amines





Reagent for the reduction of conjugated double bonds





Reagent for the preparation of organozinc (Negishi) reagents





Safety:


Zinc is relatively non-toxic, although in large amounts it can be harmful.




References:


1) Patent Reference: WO2014149164, page 211, (23.7 MB)

2) Patent Reference: WO2016023832, page 71, (3.2 MB)

3) Patent Reference: WO2015140133, page 87, (11.7 MB)

4) www.sigmaaldrich.com: Zinc - dust (link)

5) Burke, S. D.; Danheiser, R. L.; Handbook of Reagents for Organic Synthesis, Oxidizing and Reducing Agents




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