New Jobs:

- Sr Med Chemist (Atomwise)

- Research Advisor (Lilly)

- Research Inv II (BMS)

- Scientist II (Thermo Fisher)

Latest Internships:

- Moderna

  (Process Chem)


  (Chem Dev)

Alkene to Alkane



Example 1

A mixture of the SM (1.38 g, 5 mmol), Zn dust (1.95 g, 30 mmol), NH4Cl (2.67 g, 50 mmol), MeOH (10 mL), and H2O (5 mL) were refluxed for 4 h. The mixture was cooled to RT, filtered, and the filtrate concentrated. The resulting residue was purified by chromatography (5:1 PE/EtOAc) to provide the product as a brown solid. [1.15 g, 83%]

[Patent Reference: WO2016023832, page 71, (3.2 MB)]