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Deoxo-Fluor

[Bis(2-methoxyethyl)aminosulfur Trifluoride]









General Information:


Structure:



CAS Number: 202289-38-1

Molecular Weight: 221.24 g/mol

Appearance: Clear yellow liquid

Density: 1.2 g/mL


Deoxo-Fluor is a nucleophilic fluorinating agent with wide use in organic chemistry. Deoxo-Fluor is more thermally stable than Diethylaminosulfur Trifluoride (DAST).




Common Uses:


Reagent for the conversion of alcohols to fluorides





Reagent for the conversion of ketones to difluorides





References:


1) WO2016010950, page 209

2) WO2016011390, page 399

3) www.sigmaaldrich.com: Deoxo-Fluor (link)

4) www.tcichemicals.com: Bis(2-methoxyethyl)aminosulfur Trifluoride (link)

5) Godhaviya, P. K.; Fluorinating Reagents: Properties, Preparation, Applications and Safety