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  (Nucleoside Chemistry)


[Bis(2-methoxyethyl)aminosulfur Trifluoride]

General Information:


CAS Number: 202289-38-1

Molecular Weight: 221.24 g/mol

Appearance: Clear yellow liquid

Density: 1.2 g/mL

Deoxo-Fluor is a nucleophilic fluorinating agent with wide use in organic chemistry. Deoxo-Fluor is more thermally stable than Diethylaminosulfur Trifluoride (DAST).

Common Uses:

Reagent for the conversion of alcohols to fluorides

Reagent for the conversion of ketones to difluorides


1) Patent Reference: WO2016010950, page 209, (18.8 MB)

2) Patent Reference: WO2016011390, page 399, (20.2 MB)

3) Deoxo-Fluor (link)

4) Bis(2-methoxyethyl)aminosulfur Trifluoride (link)

5) Godhaviya, P. K.; Fluorinating Reagents: Properties, Preparation, Applications and Safety