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(Diethylaminosulfur Trifluoride)

Other Names:

N,N-Diethylaminosulfur trifluoride

(Diethylamino)sulfur trifluoride


General Information:


CAS Number: 38078-09-0

Molecular Weight: 161.19 g/mol

Appearance: Colorless oil

Boiling Point: 30-32 C at 3 mmHg

Density: 1.22 g/mL

Diethylaminosulfur trifluoride (DAST) is a nucleophilic fluorinating agent with wide use in organic chemistry. Deoxo-Fluor is more thermally stable alternative to DAST.

Common Uses:

Fluorinating agent for converting alcohol to fluorides

Fluorinating agent for converting aldehydes to geminal difluorides

Fluorinating agent for converting ketones to geminal difluorides


1) WO2016011930, page 160

2) WO2014201173, page 377

3) WO2016011930, page 152

4) Wikipedia: Diethylaminosulfur trifluoride (link)

5) (Diethylamino)sulfur trifluoride (link)

6) Godhaviya, P. K.; Fluorinating Reagents: Properties, Preparation, Applications and Safety