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Oxalyl Chloride


Other Names:

Ethanedioyl dichloride







General Information:


Structure:



CAS Number: 79-37-8

Molecular Weight: 126.93 g/mol

Appearance: Colorless liquid

Melting Point: -12 C

Boiling Point: 63-64 C

Density: 1.48 g/mL




Common Uses:


Reagent for the conversion of carboxylic acids to acid chlorides






Reagent in Swern Oxidations (converts alcohols to aldehydes or ketones)






Safety:


Oxalyl chloride is very toxic and corrosive. It is severely irritating to eyes, skin, and the respiratory tract. Oxalyl chloride reacts violently with water.




References:


1) Patent Reference: WO2010038081, page 138, (33.8 MB)

2) Patent Reference: WO2012129338, page 85, (12.0 MB)

3) Patent Reference: WO2010016005, page 120, (11.3 MB)

4) Patent Reference: WO2016011390, page 112, (20.2 MB)

5) Wikipedia: Oxalyl chloride (link)

6) www.sigmaaldrich.com: Oxalyl chloride (link)

7) Pearson, A. J.; Roush, W. R.; Handbook of Reagents for Organic Synthesis; Activating Agents and Protecting Groups