New Jobs:

- Scientist (Ribometrix)

- Sr Scientist (Goldfinch Bio)

- Scientific Leader (GSK)

- Chemistry RA (DiCE)

Latest Internships:

- Cayman Chemical

  (Bio-Organic Chemistry)

- Complete Genomics



(Dimethyl sulfoxide)

Other Names:

Methyl sulfoxide

General Information:


CAS Number: 67-68-5

Molecular Weight: 78.13 g/mol

Appearance: Colorless liquid

Melting Point: 16-19 C

Boiling Point: 189 C

Density: 1.10 g/mL

Dimethyl sulfoxide (DMSO) is a polar aprotic solvent that can dissolve a wide range of organic compounds. The high dissolving power of DMSO makes deuterated DMSO (DMSO-d6) a common solvent for NMR. One of the major drawbacks of DMSO is the difficulty of removal after a reaction. Its high boiling point (189 C) makes removal by rotovap very difficult. DMSO is also used as a reagent in a variety of different reactions.

Common Uses:

Reagent in Swern oxidations (conversion of alcohols to their corresponding ketones or aldehydes)


DMSO readily penetrates the skin.


1) Patent Reference: WO2016011390, page 112, (20.2 MB)

2) Patent Reference: WO2010016005, page 120, (11.3 MB)

3) Wikipedia: Dimethyl sulfoxide (link)

4) Dimethyl sulfoxide (link)