Manganese Dioxide

Other Names:

Manganese(IV) oxide

General Information:

Structure:

MnO2

CAS Number: 1313-13-9

Molecular Weight: 86.94 g/mol

Appearance: Black solid

Manganese(IV) oxide (MnO2) is a reagent typically used for the oxidation of allylic or benzylic alcohols to their corresponding aldehyde or ketone.

Common Uses:

Reagent for the oxidation of alcohols to aldehydes

Procedure excerpt:

To a solution of the SM (10 g, 63.3 mmol) in DCM (150 mL) was added activated MnO2 (38 g, 443 mmol). The reaction mixture was stirred at RT overnight. The solids were . . .

[full procedure]

Reagent for the oxidation of alcohols to ketones

Procedure excerpt:

To a solution of the SM (100 g, 371.5 mmol) in CHCl3 (200 mL) was added MnO2 (322.9 g, 3.715 mol). The reaction mixture was stirred at 60 C for 12 h. After cooling . . .

[full procedure]

References:

1) Patent Reference: WO2013134298, page 40 , (4.1 MB)

2) Patent Reference: WO2015140133, page 90, (11.7 MB)

3) Wikipedia: Manganese dioxide (link)

4) www.sigmaaldrich.com: Manganese(IV) oxide (link)

5) Burke, S. D.; Danheiser, R. L.; Handbook of Reagents for Organic Synthesis, Oxidizing and Reducing Reagents