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Benzyl Alcohol


Other Names:

Phenylmethanol

Phenylcarbinol

Benzenemethanol

BnOH




General Information:


Structure:




CAS Number: 100-51-6

Molecular Weight: 108.14 g/mol

Appearance: Colorless liquid

Melting Point: -15 C

Boiling Point: 205 C

Density: 1.045 g/mL at 25 C

Acidity (pKa): 15.40


Benzyl alcohol is generally used as a reagent in organic chemistry, although in some other industries it finds common use as a solvent.




Common Uses:


Nucleophilic reagent for SNAr reactions




Reagent for forming Cbz protected amines in Curtius rearrangements





Safety:


Benzyl alcohol is highly irritating and damaging to the eye. It is not known to be a carcinogen, teratogen, or reproductive hazard. Benzyl alcohol has a low acute toxicity.




References:


1) WO201026121, page 59

2) WO2016020526, page 58

3) Wikipedia: Benzyl alcohol (link)

4) www.sigmaaldrich.com: Benzyl alcohol (link)

5) www.alfa.com: 41218 Benzyl alcohol, ACS, 99+% (link)