p-TsCl

(p-Toluenesulfonyl Chloride)

Other Names:

4-Toluenesulfonyl chloride

4-methylbenzenesulfonyl chloride

Tosyl chloride

TsCl

General Information:

Structure:

CAS Number: 98-59-9

Molecular Weight: 190.65 g/mol

Appearance: White solid

Melting Point: 65-69 C

Boiling Point: 134 C at 10 mmHg

Common Uses:

Reagent for converting alcohols to tosylates

Reagent for converting alcohols to chlorides

Procedure excerpt:

To a 50 mL RBF was added the SM (612 mg, 1.65 mmol) in DCM (8.25 mL). DIEA (0.574 mL, 3.30 mmol) was added, followed by TsCl (378 mg, 1.98 mmol). The reaction . . .

[full procedure]

References:

1) Patent Reference: WO2015051043, page 85, (9.7 MB)

2) Wikipedia: 4-Toluenesulfonyl chloride (link)

3) www.sigmaaldrich.com: p-Toluenesulfonyl chloride (link)