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Raney Nickel










General Information:


CAS Number: 7440-02-3

Appearance: Grey powder




Common Uses:


Catalyst for the reduction of nitro groups to amines



Procedure excerpt:

To a shaker flask was added the SM (crude, 32.4 g, 138 mmol), EtOH (100 mL), and Raney Ni (1.00 g, 17.04 mmol). The flask was charged with H2 (275 kPa) and . . .

[full procedure]




Catalyst for the reduction of nitrile groups to amines




Procedure excerpt:

To a solution of the SM (6.0 g, 22.0 mmol) in MeOH (60 mL) was added Raney Ni (6.0 g). The reaction was stirred under H2 at 70 psi for 16 h, after which time . . .

[full procedure]




Safety:


Raney nickel is a pyrophoric material and needs to be handled under an inert atmosphere.




References:


1) Patent Reference: WO2013134298, page 42, (4.1 MB)

2) Patent Reference: WO2014149164, page 214, (23.7 MB)

3) Wikipedia: Raney nickel (link)

4) www.sigmaaldrich.com: Raney-Nickel (link)