Diethylzinc

Other Names:

Zincdiethyl

General Information:

Structure:

CAS Number: 557-20-0

Molecular Weight: 123.50 g/mol

Appearance: Colorless liquid

Melting Point: -28 C

Boiling Point: 117 C

Density: 1.205 g/mol

Common Uses:

Reagent in Simmons-Smith cyclopropanation reactions

Procedure excerpt:

To a solution of diethylzinc (1.0M in hexane, 46 mL, 46 mmol) in DCM (200 mL) was added dropwise a solution of TFA (3.54 mL, 46 mmol) in DCM (50 mL) at 0 C over 30 min. . . .

[full procedure]

Safety:

Diethylzinc can ignite upon exposure to air and should be handled under an inert atmosphere. Diethylzinc reacts violently with water.

References:

1) Patent Reference: WO2015129926, page 109, (21.5 MB)

2) Coates, R. M.; Denmark, S. E.; Handbook of Reagents for Organic Synthesis, Reagents, Auxiliaries, and Catalysts for C-C Bond Formation

3) Wikipedia: Diethylzinc (link)

4) www.sigmaaldrich.com: Diethylzinc solution (link)