Ketone to Methylene

Common Conditions:

Wolff-Kishner

The Wolff-Kishner conditions typically involve a strong base and heating, therefore base sensitive substrates may not be well tolerated. The reaction produces N2 gas as a by-pdt.

Examples

Mechanism

Reaction Map:

The reaction map is intended to provide insight into possible reactions one step before and after the title reaction. It also serves as an alternative way to navigate the website, and as a means of coming up with retrosynthetic ideas. Click on the reaction arrow to visit the page.