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PyBOP


Other Names:

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium

    hexafluorophosphate






General Information:


Structure:



CAS Number: 128625-52-5

Molecular Weight: 520.40 g/mol

Appearance: White solid




Common Uses:


Reagent for amide couplings



Procedure excerpt:

A mixture of the acid (200 mg, 0.81 mmol), the amine (120 mg, 1.0 mmol), and TEA (0.29 mL, 1.6 mmol) in DMF (4 mL) was treated with PyBOP (380 mg, 1.0 mmol). . . .

[full procedure]




References:


1) Patent Reference: WO2015105749, page 89, (11.4 MB)

2) Wikipedia: PyBOP (link)

3) www.sigmaaldrich.com: PyBOP (link)