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DHP

(Dihydropyran)


Other Names:

3,4-Dihydro-2H-pyran






General Information:


Structure:



CAS Number: 110-87-2

Molecular Weight: 84.12 g/mol

Appearance: Colorless liquid

Melting Point: -70 C

Boiling Point: 86 C

Density: 0.922 g/mL


Dihydropyran (DHP) is an organic compound commonly used to install tetrahydropyranyl (THP) protecting groups on alcohols and amines.




Common Uses:


Reagent for installing THP protecting groups on alcohols





Reagent for installing THP protecting groups on amines





References:


1) WO2005082859, page 296

2) WO2016011390, page 217

3) Pearson, A. J.; Roush, W. R.; Handbook of Reagents for Organic Synthesis; Activating Agents and Protecting Groups

4) Wikipedia: Dihydropyran (link)

5) www.sigmaaldrich.com: 3,4-Dihydro-2H-pyran (link)