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TMP

(2,2,6,6-Tetramethylpiperidine)









General Information:


Structure:



CAS Number: 768-66-1

Molecular Weight: 141.25 g/mol

Appearance: Clear liquid

Boiling Point: 152 C

Density: 0.837 g/mL




Common Uses:


Precursor in the making lithium tetramethylpiperidide (LTMP)



Procedure excerpt:

To a solution of 2,2,6,6-tetramethylpiperidine (997 mL, 5.87 mol) in dry THF (6 L) under N2 at 0 C was added n-BuLi (2.5 M in hexanes, 2.35 L, 5.87 mol) via an addition funnel . . .

[full procedure]




References:


1) Patent Reference: WO2012129344, page 124, (7.3 MB)

2) Wikipedia: 2,2,6,6-Tetramethylpiperidine (link)

3) www.sigmaaldrich.com: 2,2,6,6-Tetramethylpiperidine (link)