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  (Nucleoside Chemistry)



Other Names:


General Information:


CAS Number: 6674-22-2

Molecular Weight: 152.24 g/mol

Appearance: Colorless to light yellow liquid

Density: 1.018 g/mL at 25 C

DBU is considered to be a non-nucleophilic base. DBU can serve as a base, catalyst, or complexing ligand in a wide variety of reactions.

Common Uses:

Reagent for conversion of alcohols to azides (DPPA + DBU)

Catalyst in some Michael addition reactions


1) Patent Reference: WO2015144799, page 343, (18.8 MB)

2) Patent Reference: WO2014110000, page 30, (2.6 MB)

3) Wikipedia: 1,8-Diazabicyclo[5.4.0]undec-7-ene (link)

4) 1,8-Diazabicyclo[5.4.0]undec-7-ene (link)

5) Reich, H. J.; Rigby, J. H.; Handbook of Reagents for Organic Synthesis, Acidic and Basic Reagents