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Cbz Deprotection

(Strong Acid)


Example 1

A solution of the SM (0.20 g, 0.43 mmol) in conc. HCl (4 mL) was stirred at RT overnight. The mixture was concentrated to dryness to provide the HCl salt of the product as a yellow solid. [140 mg, 75%]

[Patent Reference: WO2010016005, page 98, (11.3 MB)]