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Trimethylsilyl Iodide


Other Names:

Iodotrimethylsilane

TMSI






General Information:


Structure:



CAS Number: 16029-98-4

Molecular Weight: 200.09 g/mol

Appearance: Colorless liquid




Common Uses:


Reagent for the Boc deprotection of amines



Procedure excerpt:

To a solution of the SM (0.16 g, 0.39 mmol) in CHCl3 (3.0 mL) was added dropwise TMSI (93 mg, 0.46 mmol) at RT. The reaction mixture was stirred at RT overnight. The mixture . . .

[full procedure]




References:


1) Patent Reference: WO2010016005, page 125, (11.3 MB)

2) Wikipedia: Trimethylsilyl iodide (link)

3) www.sigmaaldrich.com: Iodotrimethylsilane (link)