Trimethylsilyl Iodide

Other Names:

Iodotrimethylsilane

TMSI

General Information:

Structure:

CAS Number: 16029-98-4

Molecular Weight: 200.09 g/mol

Appearance: Colorless liquid

Common Uses:

Reagent for the Boc deprotection of amines

Procedure excerpt:

To a solution of the SM (0.16 g, 0.39 mmol) in CHCl3 (3.0 mL) was added dropwise TMSI (93 mg, 0.46 mmol) at RT. The reaction mixture was stirred at RT overnight. The mixture . . .

[full procedure]

References:

1) Patent Reference: WO2010016005, page 125, (11.3 MB)

2) Wikipedia: Trimethylsilyl iodide (link)

3) www.sigmaaldrich.com: Iodotrimethylsilane (link)