New Jobs:

- Scientist (Aduro)

- Sr Scientist (Merck)

- Principal Inv (Deciphera)

- Sr Chemist (Agilent)

Latest Internships:

- AMRI

  (Chem Dev)

- Takeda

  (Chemistry)



Titanium Isopropoxide


Other Names:

Tetraisopropyl orthotitanate

Titanium tetraisopropoxide

TTIP





General Information:


Structure:



CAS Number: 546-68-9

Molecular Weight: 284.22 g/mol

Appearance: Colorless liquid

Melting Point: 14-17 C

Boiling Point: 232 C

Density: 0.96 g/mL




Common Uses:


Lewis acid in reductive aminations



Procedure excerpt:

A mixture of the SM (260 mg, 0.79 mmol), PMB-NH2 (162 mg, 1.18 mmol), and Ti(iPrO)4 (168 mg, 1.58 mmol) in THF (10 mL) was stirred in a microwave reactor at 100 C . . .

[full procedure]




References:


1) Patent Reference: WO2016011390, page 104, (20.2 MB)

2) Wikipedia: Titanium isopropoxide (link)

3) www.sigmaaldrich.com: Titanium(IV) isopropoxide (link)