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Other Names:


General Information:


CAS Number: 25015-63-8

Molecular Weight: 127.98 g/mol

Density: 42-43 C

Pinacolborane is a reagent typically used to form boronic esters. The boronic esters are usually formed by either Pd-catalyzed borylation or hydroboration. Bis(pinacolato)diboron is much more commonly used than pinacolborane for the Pd-catalyzed formation of boronic esters. Pinacolborane, however, is a more atom-economical boron source than bis(pinacolato)diboron.

Common Uses:

Reagent for the formation of pinacol boronate esters via Pd-catalyzed borylation

Reagent for the formation of pinacol boronate esters via hydroboration


Pinacolborane is air and moisture sensitive. Incompatible with strong oxidizing agents, strong acids, bases, water, and alcohols.


1) 4,4,5,5-Tetramethyl-1,3,2-dioxaborolane (link)

2) Pinacolborane (link)

3) K. L. Billingsley, S. L. Buchwald, J. Org. Chem., 2008, 73, 5589-5591.