Isopropoxyboronic Acid Pinacol Ester

Other Names:

2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Isopropyl pinacolyl borate

General Information:

Structure:

CAS Number: 61676-62-8

Molecular Weight: 186.06 g/mol

Appearance: Colorless liquid

Density: 0.912 g/mL at 25 C

Common Uses:

Reagent for the formation of pinacol boronate esters (typically used in Suzuki reactions)

Procedure excerpt:

. . . The mixture was stirred at -78 C for 30 min, after which time was added isopropoxyboronic acid pinacol ester (1.36 mL, 6.67 mmol). The reaction mixture was stirred at -78 C . . .

[full procedure]

References:

1) Patent Reference: WO2015144799, page 123, (18.8 MB)

2) www.sigmaaldrich.com: 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane) (link)

3) www.alfa.com: L17278 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 98% (link)

4) www.chemspider.com: 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (link)