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  (Nucleoside Chemistry)


General Information:


CAS Number: 142-82-5

Molecular Weight: 100.21 g/mol

Appearance: Colorless liquid

Melting Point: -91 C

Boiling Point: 98 C

Density: 0.684 g/mL at 25 C

Common Uses:

Solvent (mobile phase) for silica gel chromatography

Procedure excerpt:

…The resulting material was purified by flash chromatography (eluting with 30-70% EtOAc/heptane) to provide the product…

Solvent/co-solvent for trituration

Procedure excerpt:

…The solid was triturated with 2:1 ether/heptane (90 mL) for 1 h, before filtering to provide the product as a white solid…


1) Patent Reference: WO2012069948, page 90, (3.9 MB)

2) Patent Reference: WO2012069948, page 63, (3.9 MB)

3) Wikipedia: Heptane (link)

4) Heptane (link)