New Jobs:

- RS I/II (Contraline)

- Scientist (EMD)

- Med Chemist (SBP)

- Scientist (Astex)

Latest Internships:

- U of Florida/France

  (Summer 2019)

- University of Iowa

  (Summer 2019)

Copper(II) Chloride

Other Names:

Cupric chloride

General Information:


CAS Number: 7447-39-4 (anhydrous)

    10125-13-0 (dihydrate)

Molecular Weight: 134.45 g/mol (anhydrous)

    170.48 g/mol (dihydrate)

Appearance: Yellow/brown solid (anhydrous)

    Blue/green solid (dihydrate)

Chemical Formula: CuCl2

Melting Point: 620 C

Common Uses:

Reagent for Sandmeyer reactions where chloride products are desired

Procedure excerpt:

To a suspension of CuCl2 (450 mg, 3.4 mmol) in ACN (8 mL) was added t-BuONO (0.52 mL, 3.9 mmol). The mixture was stirred for 5 min then a solution of the SM (830 mg, 2.8 mmol) . . .

[full procedure]


1) Patent Reference: WO2015105749, page 97, (11.4 MB)

2) Coates, R. M.; Denmark, S. E.; Handbook of Reagents for Organic Synthesis, Reagents, Auxiliaries, and Catalysts for C-C Bond Formation

3) Wikipedia: Copper(II) chloride (link)

4) Copper(II) chloride (link)