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2,6-Lutidine


Other Names:

2,6-Dimethylpyridine







General Information:


Structure:



CAS Number: 108-48-5

Molecular Weight: 107.15 g/mol

Appearance: Clear liquid

Melting Point: -6 C

Boiling Point: 143-145 C

Density: 0.92 g/mL




Common Uses:


Basic reagent/catalyst in the TBS protection of alcohols using TBS-OTf



Procedure excerpt:

A mixture of the SM (2.0 g, 10.0 mmol), 2,6-lutidine (2.13 g, 19.9 mmol), TBSOTf (3.1 g, 14.9 mmol), and DCM (30 mL) was stirred at RT for 2 h. The reaction . . .

[full procedure]




References:


1) Wikipedia: 2,6-Lutidine (Link)

2) www.sigmaaldrich.com: 2,6-Lutidine (Link)

3) Reich, H. J.; Rigby, J. H.; Handbook of Reagents for Organic Synthesis, Acidic and Basic Reagents