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MTBE

(Methyl tert-butyl ether)


Other Names:

tert-Butyl methyl ether

2-Methoxy-2-methylpropane





General Information:


Structure:



CAS Number: 1634-04-4

Molecular Weight: 88.15 g/mol

Appearance: Colorless liquid

Melting Point: -109 C

Boiling Point: 55-56 C

Density: 0.74 g/mL at 25 C




Common Uses:


Solvent for extractions



Procedure excerpt:

. . . concentrated to a brown solid. The resulting material was triturated in MTBE then EtOAc to provide the product . . .

[full procedure]




Solvent for triturations



Procedure excerpt:

. . . was quenched onto H2O (150 mL) and extracted with MTBE (3 x 50 mL). The combined org extracts were . . .

[full procedure]




Solvent for azeotroping



Procedure excerpt:

. . . The resulting eluent was concentrated in vacuo and azeotroped with MTBE to provide the product as a formate salt . . .

[full procedure]




Safety:


Methyl tert-butyl ether (MTBE) is a flammable liquid.




References:


1) Patent Reference: WO2010035166, page 56, (3.2 MB)

2) Patent Reference: WO2010032200, page 133, (6.2 MB)

3) Patent Reference: WO2016014463, page 111, (6.7 MB)

4) Wikipedia: Methyl tert-butyl ether (link)

5) Aldrich: tert-Butyl methyl ether (link)