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Cyclohexane










General Information:


Structure:



CAS Number: 110-82-7

Molecular Weight: 84.16 g/mol

Appearance: Colorless liquid

Melting Point: 6.5 C

Boiling Point: 81 C


Cyclohexane is a colorless liquid with a detergent-like odor. It is used occasionally in organic chemistry as a solvent/co-solvent for purposes such as silica gel purifications or compound recrystallizations.


Common Uses:


Solvent/co-solvent (mobile phase) for silica gel chromatography



Procedure Excerpt:

. . . The resulting material was purified by silica gel column chromatography (30-50% EtOAc/cyclohexane) to provide the product . . .

[full procedure]




Safety:


Cyclohexane is a flammable liquid.




References:


1) Patent Reference: WO2015177325, page 71, (4.3 MB)

2) Wikipedia: Cyclohexane (link)

3) www.sigmaaldrich.com: Cyclohexane (link)