New Jobs:

- Scientist (MilliporeSigma)

- Sr Chemist (Nanoly)

- Research Assoc (Gilead)

- Sr RS (Saimerak Pharma)

Latest Internships:

- Moderna

  (Discovery Chemistry)

- Merck

  (Chemistry)



DCE

(1,2-Dichloroethane)


Other Names:

Ethylene dichloride

Ethane dichloride





General Information:


Structure:



CAS Number: 107-06-2

Molecular Weight: 98.96 g/mol

Appearance: Colorless liquid

Melting Point: -35 C

Boiling Point: 83 C

Density: 1.256 g/mL at 25 C


1,2-Dichloroethane (DCE) is a generally used as a solvent in organic chemistry. DCE can act as an alkylating agent in the presence of a suitable nucleophile and under the right reaction conditions.




Common Uses:


Solvent for reactions



Procedure excerpt:

To a solution of the SM (crude) in DCE (50 mL) at 0 C was added NaBH(OAc)3 (3.6 g, 17.1 mmol). The reaction mixture was stirred at 0 C for 2 h, after which time . . .

[full procedure]




Safety:


1,2-Dichloroethane (DCE) is a toxic, carcinogenic, and highly flammable liquid.




References:


1) Patent Reference: WO2016014463, page 64, (6.7 MB)

2) Wikipedia: 1,2-Dichloroethane (link)

3) www.sigmaaldrich.com: 1,2-Dichloroethane (link)