n-Butanol

Other Names:

1-Butanol

Butyl alcohol

Butan-1-ol

General Information:

Structure:

CAS Number: 71-36-3

Molecular Weight: 74.12 g/mol

Appearance: Colorless liquid

Melting Point: -90 C

Boiling Point: 116-118 C

Appearance: 0.81 g/mL

n-Butanol is sometimes a useful substitute as a solvent for ethanol or isopropanol because of its higher boiling point (118 C).

Common Uses:

Solvent for reactions

Procedure excerpt:

A mixture of the aryl chloride (A) (1 Kg, 7.72 mol), the amine (B) (1.5 Kg, 10.03 mol), TEA (3.23 L, 23.2 mol), and n-BuOH (8 L) were stirred at reflux . . .

[full procedure]

Safety:

In general, n-butanol is considered to be of low toxicity to humans. For example, it is even used in consumer products such as cosmetics. n-Butanol is a flammable liquid but less flammable than many other common solvents.

References:

1) Patent Reference: WO2012129344, page 123, (7.3 MB)

2) Wikipedia: n-Butanol (link)

3) www.sigmaaldrich.com: 1-Butanol (link)