(Boron Trifluoride Diethyl Etherate)
Other Names:
Boron trifluoride ethyl etherate
Structure:
CAS Number: 109-63-7
Molecular Weight: 141.93 g/mol
Appearance: Light yellow liquid
Melting Point: -58 C
Boiling Point: 126-129 C
Density: 1.15 g/mL
Boron trifluoride diethyl etherate (BF3-OEt2) is a convenient, easy to handle source of boron trifluoride (BF3). BF3-OEt2 is a liquid, whereas BF3 is a gas.
Reagent for SEM deprotection
Procedure excerpt:
To a solution of the SM (0.85 g, 1.8 mmol) in DCM (10 mL) at 0 C was added BF3-OEt2 (2.33 mL, 18.4 mmol). The reaction was allowed to warm to RT and stir for 2 h. . . .
Keep BF3-OEt2 away from moisture and oxidizing agents.
1) Patent Reference: WO2012149280, page 63, (4.1 MB)
2) www.sigmaaldrich.com: Boron trifluoride diethyl etherate (link)
3) Reich, H. J.; Rigby, J. H.; Handbook of Reagents for Organic Synthesis, Acidic and Basic Reagents